Current Projects and News

Current Projects

  • Development of an impedance spectrometric method for assessing cell growth and protein / blood cell occupancy of membranes in hollow-fiber bioreactors and dialyzers – Support initiative “Medizintechnik Bayern” (Medical technology Bavaria)
  • Flexible robot-based platform for automated production of nanoparticles (German press release)
  • In vitro test procedures to evaluate the effectiveness of immunological therapies for malignant melanoma (Press release)
  • Cryopreservation of three-dimensional cell cultures
  • Nanoparticle-based contrast agent for multimodal in vivo diagnostics
  • Tumor diagnostics for individualized therapy

 

Finalized projects:

Biomaterials for Organ and Tissue Regeneration –
New Technologies and Future Prospects

Book-Cover Biomaterials For Organ And Tissue Regeneration
© Elsevier
Paperback ISBN: 9780081029060
eBook ISBN: 9780081029077

The book describes biomaterials-related technologies, providing comprehensive information on the properties and use of biomaterials in tissue regeneration and in vitro modelling of organs.

In the introduction, properties and forms of novel biomaterials are described and off-shoot technologies such as Biorobotics, Bioinks or Bioprinting are discussed. In addition to a summary of physico-chemical properties, methods used for the analysis of biostructural characterization and surface functionalization of biomaterials are reviewed. Furthermore, properties of modern cell sources such as stem cells and immune cells with relevance for regenerative medicine are described. In addition, basic principles of cellular communication with biomaterials are addressed. Following, current organ-specific application areas of biomaterials are summarized. These include cardiovascular and pancreatic tissue engineering approaches as well as in vitro modelling of the blood-brain barrier, lung, kidney or bladder. With the article "Bioartificial good", the Fraunhofer ISC has made a further contribution in this context.

The book concludes with a summary of novel technologies, especially with regard to biomaterials and their significance for tissue and organ regeneration. Besides nanomaterials and hydrogels, focus is on biomaterials and their application in microfluidics, in organ-on-a-chip systems or their integration into dynamic bioreactors.

Press Releases

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  • Around 60 international experts met on November 7 at the Fraunhofer Institute for Silicate Research ISC in Würzburg to report on the state of the art in the field of 3D tissue models and prevention of animal experiments in the development of pharmaceuticals and medical devices. The Forum MedTech Pharma and the Fraunhofer Translational Center for Regenerative Therapies TLC-RT had invited to the conference, which is scheduled to take place annually.

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  • The WHO reports an estimated 429,000 malaria deaths each year. The disease mostly affects tropical and subtropical regions and in particular the African continent. The Fraunhofer Institute for Silicate Research ISC teamed up with the Fraunhofer Institute for Molecular Biology and Applied Ecology IME and the Institute of Tropical Medicine at the University of Tübingen for a new test method to detect malaria parasites in blood. The idea of the research project “NanoFRET” is to develop a highly sensitive and reliable rapid diagnostic test so that patient treatment can begin as early as possible.

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Events

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  • Fraunhofer Translational Center Regenerative Therapies TLC-RT / 05/26/2020 - 05/28/2020

    Pluripotent Stem Cell Training

    iPSC Training
    © Stemcell Technologies

    Pluripotent stem cell (PSC) research is an expanding field that has the potential to change the way human diseases are studied and treated. With our three-day course, you can learn the techniques and protocols to help get your PSC research started. Guided by experts from STEMCELL and the Fraunhofer Institute, you will gain skills to successfully derive and maintain high-quality human induced pluripotent stem (iPS) cells from somatic cells and differentiate them towards specialized cell types. In this immersive learning experience, you will have the opportunity to experience adaptive practical sessions and engage with PSC experts from the Fraunhofer Institute.

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