Fraunhofer Translational Center Regenerative Therapies TLC-RT

The Fraunhofer Translational Center Regenerative Therapies TLC-RT develops new cell based tissue models and test systems, scalable manufacture processes, prototypes and biological vascularized implants. Therefore, besides accelerating cost efficient drug development, TLC-RT contributes to promoting the 3R principles.

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Online Seminar: Tissue Engineering - Basics of 3D cell culture

From October 16 - 18, Fraunhofer ISC (in cooperation with the Chair of Tissue Engineering (TERM), University Hospital Würzburg and Fraunhofer ITEM) will host a three-day online seminar on tissue engineering.

Among other things, the seminar will provide insights into the fundamentals of 3D cell culture for tissue engineering - both from a biological and a materials science perspective.

There will also be plenty of information on practical application.


Press Release / 3.4.2023

Project "SAPs4Tissue" launched

Human tissue models with customized biomaterials


Press Release March 01, 2023

Innovative in vitro eye irritation test to replace standard animal testing

Lectures / Congresses

»Impedance based prediction of eye irritation«
WC12 Congress on Alternatives and Animal Use in the Life Sciences
Aug. 27-31, 2023

»Ultrasensitive impedance spectroscopy to replace the Draize eye test«
ifscc / Sept. 4-7, 2023

»Human 3D Conjunctival model for eye drop testing«
EuroTox / Sept. 10-13, 2023

DOG / 9/28 - 10/1/2023

»Intestinal tissue models representing the in vivo situation to a high degree«
EMBL Symposium / Oct. 18-21, 2023


Scientific publication / 15.7.2023

Process automation

Establishing and testing a robot-based platform to enable the automated production of nanoparticles in a flexible and modular way

Analysis of the effect of plant oils

Together with its research partner Kneipp, the TLC-RT team is investigating protective as well as regenerative effects of various plant oils on in vitro skin models developed in-house. These screenings can be carried out quickly, flexibly and without animal testing.

Press Release / 29.7.2022


DFG Animal Welfare Prize for the Fraunhofer Translational Center for Regenerative Therapies

Fields of Activity and Teaching



  • 3D Bioprinting
  • Regenerative Biomaterials
  • In vitro and in vivo diagnostics
  • Drug Delivery
  • Future Technologies

Lab Automation and Bioreactor Technologies


In vitro Test Systems

  • Standardized in vitro test systems
  • Disease models
  • hiPSC technologies

Preclinical and Clinical Development

  • Implants / GMP
  • Preclinical / GLP

Chair of Tissue
Engineering and
Regenerative Medicine

  • Development of supporting structures
  • Cell culture techniques

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Project TheraVision – Innovative therapy against cancer

In the "TheraVision" project, five Fraunhofer Institutes have set themselves the goal of establishing a widely applicable platform technology for an innovative, sustainable cancer therapy that combines cancer-killing viruses and immunotherapy. The activation of the immune system against the degenerated tumor cells is a novel promising therapeutic approach.

News and Events


Online Seminar Tissue Engineering – Basics of 3D cell culture 2023

The Fraunhofer seminar on Tissue engineering will provide a compact review of the basics of tissue engineering – in terms of biology, bioprocessing and materials science. The three-day online seminar will also offer an insight into practical applications at Fraunhofer, ranging from personalized test systems to the development and approval of cell-based therapies.
more info


Workshop 3D Bioprinting

Fraunhofer ISC, in collaboration with the company REGENHU, will provide a compact overview of the basics of 3D bioprinting. The two-day hybrid workshop (online/in person) will offer live demonstrations as well as lectures and bookable slots for supervised working with the new generation of REGENHU printing device (bioprinting combined with melt electrospinning) including testing of your individual materials.
more info


Biofabrication meets Infection

PhD students of the SFB/TRR 225 Collaborative Research Centre “Biofabrication” and the GRK2157 "3D Infect" research group are organizing an amazing joint international symposium "Biofabrication meets Infection", which will take place on the 23 – 25. November 2022 at the Rudolf Virchow Center in Wuerzburg (Germany). Numerous high-profile speakers have already confirmed their participation. This international conference will focus primarily on topics of biofabrication and complex tissue models.
more info


CellME 2022

Empowering breakthroughs for life: At the CellME Forum, you can meet providers of advanced solutions for cell manufacturing technologies, gene- and cell-based therapies, and regenerative medicine, share expertise, and see research facilities in operation.
more info

Project APRONA

Flexible robot-based platform for automated production of nanoparticles.

Your local contact

Florian Groeber-Becker

Contact Press / Media

Dr. Florian Groeber-Becker

Director of TLC-RT

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Neunerplatz 2
97082 Würzburg, Germany

Phone + 49 931 4100-136

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Sofia Dembski

Contact Press / Media

Dr. Sofia Dembski

Deputy Director of TLC-RT / Head of Biomaterials

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Neunerplatz 2
97082 Würzburg, Germany

Phone +49 931 4100-516