Research against the corona virus

The Fraunhofer ISC with its Translational Center for Regenerative Therapies is working together with virologists from the University of Würzburg to combat the virus: with rapid tests of potential active substances against SARS-CoV-2.

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Lab Automation and Bioreactor Technologies

The incubator and bioreactor systems developed at TLC-RT have a modular structure and can be adjusted to a wide variety of culture conditions.

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Biomaterials

The TLC-RT develops synthetic as well as bio-logically based materials, e. g. (μ- and nano-) particles, fibers, coatings for regenerative medicine, tissue engineering and diagnostics. One of the core tasks is to cover the entire value chain, starting from R&D-tasks over process up-scaling, pre-clinic evaluation to the clinical phases.

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Clinical Development

The production of novel drugs and medical devices is subject to high quality requirements. By fulfilling current regulatory guidelines, the TLC-RT ensures the highest level of patient safety for these new, innovative therapies.

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Test Systems and 3D Tissue Models

3D tissue models includes model systems of healthy and diseased organs to study pathogenic mechanisms and to test and evaluate new drugs. Picture shows a full skin model.

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Fraunhofer Translational Center Regenerative Therapies TLC-RT

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Fraunhofer Translational Center Regenerative Therapies TLC-RT

The Fraunhofer Translational Center Regenerative Therapies TLC-RT develops new cell based tissue models and test systems, scalable manufacture processes, prototypes and biological vascularized implants. Therefore, besides accelerating cost efficient drug development, TLC-RT contributes to promoting the 3R principles.

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Research against the corona virus

Tissue models for rapid drug testing

 

Partner for EU projects

Fraunhofer ISC has an excellent record of accomplishments in European collaboration and can build on a large international network of research partners from industry as well as research.

Fields of Activity and Teaching

 

Biomaterials

  • Regenerative Biomaterials
  • In vitro and in vivo diagnostics
  • Drug Delivery
  • Future Technologies
 

Lab Automation and Bioreactor Technologies

 

In vitro Testsystems

  • Standardized in vitro test systems
  • Disease models
  • hiPSC technologies
 

Preclinical and Clinical Development

  • Implants / GMP
  • Preclinical / GLP
 

Chair of Tissue
Engineering and
Regenerative Medicine

  • Development of supporting structures
  • Cell culture techniques
 

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Project TheraVision – Innovative therapy against cancer

In the "TheraVision" project, five Fraunhofer Institutes have set themselves the goal of establishing a widely applicable platform technology for an innovative, sustainable cancer therapy that combines cancer-killing viruses and immunotherapy. The activation of the immune system against the degenerated tumor cells is a novel promising therapeutic approach.

News and Events

8.4.2020

Research against the corona virus -
tissue models for rapid drug testing

The pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is placing unprecedented restrictions on public life and economy. The global research efforts to fill the knowledge gaps regarding the new pathogen and to develop effective therapies are correspondingly large. In Wuerzburg, too, researchers from the Fraunhofer Translational Center for Regenerative Therapies are working together with the virologist Prof. Dr. Bodem from the University of Wuerzburg to identify active substances against the virus.
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19.11.2019

New ways to avoid animal testing –
Human 3D Tissue Models Conference in Würzburg

Around 60 international experts met on November 7 at the Fraunhofer Institute for Silicate Research ISC in Würzburg to report on the state of the art in the field of 3D tissue models and prevention of animal experiments in the development of pharmaceuticals and medical devices. The Forum MedTech Pharma and the Fraunhofer Translational Center for Regenerative Therapies TLC-RT had invited to the conference, which is scheduled to take place annually.
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7.11.2019

Human 3D Tissue Models: 3R in the Light of Drug Development and MDR

At the conference, representatives of research institutes, clinics and industry will present novel human 3D tissue models and test systems, applied in pharma research and development as well as for medical device testing. Upcoming technologies such as Bio-Printing or Organ-on-a-Chip will also be demonstrated.
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Project APRONA

Flexible robot-based platform for automated production of nanoparticles.

Your local contact

Marco Metzger

Contact Press / Media

PD Dr. Marco Metzger

Director TLC-RT

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Röntgenring 11
97070 Würzburg, Germany

Phone +49 931 3186686

Oliver Pullig

Contact Press / Media

PD Dr. Oliver Pullig

Deputy Director of TLC-RT / Head of Clinical Development

Translational Center Regenerative Therapies TLC-RT
Röntgenring 11
97070 Würzburg, Germany

Phone +49 931 31-83748