Fraunhofer Translational Center Regenerative Therapies TLC-RT

Fraunhofer Translational Center Regenerative Therapies TLC-RT

3D Bioprinting technology
© RegenHU

3D Bioprinting

Automatized and standardized fabrication of complex living tissues

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© RegenHU

DFG Animal Welfare Award 2022
© AdobeStock

DFG Animal Welfare Prize 2022

Award for the TLC-RT team for research on alternatives to animal experiments

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© AdobeStock

Antiviral effect of plant extracts
© Evonik

Antiviral effect of plant extracts

Proof with in vitro cell cultures successful

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© Evonik

Lab Automation and Bioreactor Technologies

The incubator and bioreactor systems developed at TLC-RT have a modular structure and can be adjusted to a wide variety of culture conditions.

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Biomaterials

The TLC-RT develops synthetic as well as bio-logically based materials, e. g. (μ- and nano-) particles, fibers, coatings for regenerative medicine, tissue engineering and diagnostics. One of the core tasks is to cover the entire value chain, starting from R&D-tasks over process up-scaling, pre-clinic evaluation to the clinical phases.

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Clinical Development

The production of novel drugs and medical devices is subject to high quality requirements. By fulfilling current regulatory guidelines, the TLC-RT ensures the highest level of patient safety for these new, innovative therapies.

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Test Systems and 3D Tissue Models

3D tissue models includes model systems of healthy and diseased organs to study pathogenic mechanisms and to test and evaluate new drugs. Picture shows a full skin model.

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Fraunhofer Translational Center Regenerative Therapies TLC-RT

The Fraunhofer Translational Center Regenerative Therapies TLC-RT develops new cell based tissue models and test systems, scalable manufacture processes, prototypes and biological vascularized implants. Therefore, besides accelerating cost efficient drug development, TLC-RT contributes to promoting the 3R principles.

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© pixabay

Press Release March 01, 2023

Innovative in vitro eye irritation test to replace standard animal testing

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© pexels

Analysis of the effect of plant oils

Together with its research partner Kneipp, the TLC-RT team is investigating protective as well as regenerative effects of various plant oils on in vitro skin models developed in-house. These screenings can be carried out quickly, flexibly and without animal testing.

 

© Fraunhofer ISC

Nanoparticles meet
Automation

Quality assurance, cost savings, occupational safety are only three of many aspects achieved in the automated production of nanoparticles. A dual-arm robot interacts with the surrounding laboratory infrastructure 24/7.

Dr. Sofia Dembski provides information on the fascinating future of Lab 4.0 in a case study on the APRONA prototype plant.

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© Milena Schlösser

Felix-Wankel-Award '21

Dr. Christian Lotz (Deputy Head of Department In Vitro Test Systems) receives this year's Felix Wankel Prize for the development of an in vitro eye irritation test.

The new method is expected to replace the Draize eye test after about 80 years and thus provide an alternative to previous animal testing.

Congratulations on this success!

Invitro Eye Test

3D Bioprinting Technology

for automatized and standardized fabrication of complex living tissues

3D Bioprinting

Press Release / 29.7.2022

Awarded!

DFG Animal Welfare Prize for the Fraunhofer Translational Center for Regenerative Therapies

DFG Animal Welfare Prize
 

© Fraunhofer ISC

Platform Technology in Life Sciences

Our team is developing absorbable RENACER® fibers that have no cyto- or genotoxicity and completely dissolve into bioactive monosilicic acid when in contact with physiological fluids.

RENACER® fiber systems

Fields of Activity and Teaching

 

© K. Dobberke for Fraunhofer ISC

Biomaterials

  • 3D Bioprinting
  • Regenerative Biomaterials
  • In vitro and in vivo diagnostics
  • Drug Delivery
  • Future Technologies
Biomaterials
 

© K. Dobberke for Fraunhofer ISC

Lab Automation and Bioreactor Technologies

Lab Automation and Bioreactor Technologies
 

© K. Dobberke for Fraunhofer ISC

In vitro Test Systems

  • Standardized in vitro test systems
  • Disease models
  • hiPSC technologies
In vitro Test systems
 

© K. Dobberke for Fraunhofer ISC

Preclinical and Clinical Development

  • Implants / GMP
  • Preclinical / GLP
Preclinical and Clinical Development
 

© K. Dobberke for Fraunhofer ISC

Chair of Tissue
Engineering and
Regenerative Medicine

  • Development of supporting structures
  • Cell culture techniques
Chair of Tissue
 

Contact or callback?

 

Contact us today without any
obligation!

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© Fraunhofer ISC

Project TheraVision – Innovative therapy against cancer

In the "TheraVision" project, five Fraunhofer Institutes have set themselves the goal of establishing a widely applicable platform technology for an innovative, sustainable cancer therapy that combines cancer-killing viruses and immunotherapy. The activation of the immune system against the degenerated tumor cells is a novel promising therapeutic approach.

Project TheraVision

News and Events

Current Projects and News

14.3.2023

Workshop 3D Bioprinting

Fraunhofer ISC, in collaboration with the company REGENHU, will provide a compact overview of the basics of 3D bioprinting. The two-day hybrid workshop (online/in person) will offer live demonstrations as well as lectures and bookable slots for supervised working with the new generation of REGENHU printing device (bioprinting combined with melt electrospinning) including testing of your individual materials.
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23.11.2022

Biofabrication meets Infection

PhD students of the SFB/TRR 225 Collaborative Research Centre “Biofabrication” and the GRK2157 "3D Infect" research group are organizing an amazing joint international symposium "Biofabrication meets Infection", which will take place on the 23 – 25. November 2022 at the Rudolf Virchow Center in Wuerzburg (Germany). Numerous high-profile speakers have already confirmed their participation. This international conference will focus primarily on topics of biofabrication and complex tissue models.
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18.10.2022

CellME 2022

Empowering breakthroughs for life: At the CellME Forum, you can meet providers of advanced solutions for cell manufacturing technologies, gene- and cell-based therapies, and regenerative medicine, share expertise, and see research facilities in operation.
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26.9.2022

EUSAAT 2022

The annual congress provides an opportunity to share scientific experiences on alternatives to the use of animals in the life sciences, to learn about EU 3Rs policy, and to discuss new approaches to implementing the 3Rs in academic education at the European and international levels.
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© Yaskawa Europe GmbH

Project APRONA

Flexible robot-based platform for automated production of nanoparticles.

Go to Press Release APRONA (in German)

Your local contact

Florian Groeber-Becker

Contact Press / Media

Dr. Florian Groeber-Becker

Director of TLC-RT

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Neunerplatz 2
97082 Würzburg, Germany

Phone +49 931 31-86669

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Sofia Dembski

Contact Press / Media

Dr. Sofia Dembski

Deputy Director of TLC-RT / Head of Biomaterials

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Neunerplatz 2
97082 Würzburg, Germany

Phone +49 931 4100-516