Fraunhofer Translational Center Regenerative Therapies TLC-RT

The Fraunhofer Translational Center Regenerative Therapies TLC-RT develops new cell based tissue models and test systems, scalable manufacture processes, prototypes and biological vascularized implants. Therefore, besides accelerating cost efficient drug development, TLC-RT contributes to promoting the 3R principles.

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Impressions from the WI3R Symposium 2024

"Research for alternatives to animal testing"

Get an insight into the first WI3R Symposium from June 5 to 7, 2024 in Würzburg. Many thanks to everyone who took part - we look forward to seeing you again at the next symposium in 2026!


Press Release / 3.4.2023

Project "SAPs4Tissue" launched

Human tissue models with customized biomaterials


Press Release March 01, 2023

Innovative in vitro eye irritation test to replace standard animal testing

3D Bioprinting Technology

for automatized and standardized fabrication of complex living tissues

Scientific publication / 15.7.2023

Process automation

Establishing and testing a robot-based platform to enable the automated production of nanoparticles in a flexible and modular way

Analysis of the effect of plant oils

Together with its research partner Kneipp, the TLC-RT team is investigating protective as well as regenerative effects of various plant oils on in vitro skin models developed in-house. These screenings can be carried out quickly, flexibly and without animal testing.

Press Release / 29.7.2022


DFG Animal Welfare Prize for the Fraunhofer Translational Center for Regenerative Therapies

Fields of Activity and Teaching



  • 3D Bioprinting
  • Regenerative Biomaterials
  • In vitro and in vivo diagnostics
  • Drug Delivery
  • Future Technologies

Lab Automation and Bioreactor Technologies


In vitro Test Systems

  • Standardized in vitro test systems
  • Disease models
  • hiPSC technologies

Preclinical and Clinical Development

  • Implants / GMP
  • Preclinical / GLP

Chair of Tissue
Engineering and
Regenerative Medicine

  • Development of supporting structures
  • Cell culture techniques

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Project TheraVision – Innovative therapy against cancer

In the "TheraVision" project, five Fraunhofer Institutes have set themselves the goal of establishing a widely applicable platform technology for an innovative, sustainable cancer therapy that combines cancer-killing viruses and immunotherapy. The activation of the immune system against the degenerated tumor cells is a novel promising therapeutic approach.

News and Events


WI3R Symposium 2024

The further development and implementation of the 3R principles represents a central task of biomedical research. In recent years, the metropolitan region of Northern Bavaria has developed into one of the leading research locations, especially for cancer and infectious diseases as well as for novel medical devices. At the same time, alternatives to animal testing have gained in importance and have found their way into biomedical research. The research location Würzburg has meanwhile become the nucleus of 3R research, in particular of alternative methods to animal experiments, within Bavaria and beyond.
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Online Seminar Tissue Engineering – Basics of 3D cell culture 2023

The Fraunhofer seminar on Tissue engineering will provide a compact review of the basics of tissue engineering – in terms of biology, bioprocessing and materials science. The three-day online seminar will also offer an insight into practical applications at Fraunhofer, ranging from personalized test systems to the development and approval of cell-based therapies.
more info

Project APRONA

Flexible robot-based platform for automated production of nanoparticles.

Your local contact

Florian Groeber-Becker

Contact Press / Media

Prof. Dr. Florian Groeber-Becker

Director of TLC-RT

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Röntgenring 12
97070 Würzburg, Germany

Phone + 49 931 4100-136

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Sofia Dembski

Contact Press / Media

Dr. Sofia Dembski

Deputy Director of TLC-RT / Head of Biomaterials

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Neunerplatz 2
97082 Würzburg, Germany

Phone +49 931 4100-516