Fraunhofer Translational Center Regenerative Therapies TLC-RT

The Fraunhofer Translational Center Regenerative Therapies TLC-RT develops new cell based tissue models and test systems, scalable manufacture processes, prototypes and biological vascularized implants. Therefore, besides accelerating cost efficient drug development, TLC-RT contributes to promoting the 3R principles.

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Sustainable biogenic materials

Silicic acids, which are found in rice and bamboo, are important for our lives because they have a biostimulating effect on the body and the environment. At Fraunhofer ISC, sustainable, biodegradable materials are being developed from silicic acid that accelerate the body's regeneration and promote health. Dr. Bastian Christ will be glad to tell you more about the sustainable synthesis of biodegradable materials for life science applications!

 

Reliable availability of epiCS® epidermis models

The Fraunhofer Translation Center for Regenerative Therapies (TLC-RT) is taking over epiCS® technology from Henkel AG & Co. KGaA, ensuring the availability of internationally standardized epidermis models. These OECD-validated tissue models offer a reliable alternative for evaluating skin reactions to chemical substances and contribute to the safety of cosmetics and pharmaceuticals.

 

Project "KITAMAKI"

Cancer Immunotherapy through Local T-Cell Activation

The "KITAMAKI" project develops innovative approaches for treating skin metastases in breast cancer through local T-cell activation using monoclonal antibodies on biocompatible RENACER®-fibers. This also provides effective treatment options for other cancers, such as malignant melanoma. Follow­ing validation, a drug prototype will be ready, offering a cost-effective and safe therapeutic option.

Presentations / Congresses

»Project ImAi: Alternatives to the Draize eye irritation test«
EUROTOX Congress (Athens), September 14-17, 2025
 

»In vitro test systems for testing natural products«
Phytotherapiekongress (Hannoversch Münden), September 25-26, 2025
 

»Enhanced Fibrosis Modeling in Human Skin Organoids through hiPSC-Derived Macrophage Integration«
GSCN Conference (Munich), October 15-17, 2025

We look forward to meeting you in person!

 

Article SOFW Journal / 29.1.2025

Sustainable beauty

The ISC biomaterial team is generating a bioresorbable RENACER® material platform for a novel vegan, biodegradable hair fixative from IPPM Technologies GmbH.

3D Bioprinting Technology

for automatized and standardized fabrication of complex living tissues

Analysis of the effect of plant oils

Together with its research partner Kneipp, the TLC-RT team is investigating protective as well as regenerative effects of various plant oils on in vitro skin models developed in-house. These screenings can be carried out quickly, flexibly and without animal testing.

Fields of Activity and Teaching

 

Biomaterials

  • 3D Bioprinting
  • Regenerative Biomaterials
  • In vitro and in vivo diagnostics
  • Drug Delivery and Future Technologies
 

Lab Automation and Bioreactor Technologies

 

In vitro Test Systems

  • Standardized in vitro test systems
  • Disease models
  • hiPSC technologies
 

Chair of Tissue
Engineering and
Regenerative Medicine

  • Development of supporting structures
  • Cell culture techniques
 

Contact or callback?

 

Contact us today without any
obligation!

Your local contact

Florian Groeber-Becker

Contact Press / Media

Prof. Dr. Florian Groeber-Becker

Director of TLC-RT

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Röntgenring 12
97070 Würzburg, Germany

Phone + 49 931 4100-136

  • Send email
Sofia Dembski

Contact Press / Media

Dr. Sofia Dembski

Deputy Director of TLC-RT / Head of Biomaterials

Fraunhofer Translational Center Regenerative Therapies TLC-RT
Neunerplatz 2
97082 Würzburg, Germany

Phone +49 931 4100-516