Fraunhofer Translational Center Regenerative Therapies TLC-RT
In addition to biomaterials, the Translational Center at Fraunhofer ISC also develops devices for the tissue engineering process and regenerative therapies.
Key focus areas include cell-material interactions, incubators and bioreactors for dynamic long-term culture of various cell types and tissues under physiological conditions. This is complemented by the development of non-invasive detection methods to monitor the viability and differentiation status of human tissues.
For tissue engineering organoids, spheroids and three dimensional tissues, it is essential to maintain the function of tissue-specific cells in vitro. This means: the microenvironment of the cells must be replicated in vivo. Conditions such as media flow, rotational stress and oscillating forces are important factors in tissue development. To this end, we develop devices such as bioreactors and specialized incubator systems for you.
Furthermore, a fully automated, robot-assisted cell culture laboratory has been implemented as a modular system, on which complex cell culture processes can be realized holistically. Individual modules can also be operated independently of each other, enabling the execution of standardized processes such as media changes or cell counting.
